BGC > Produktsuche > 3-Hydroxy-benzoic acid 1,1′-(3-fluoro-1,2-phenylene) ester | 1223397-11-2

Molecular Formula: C20H13FO6
Hazard Symbols: N
WGKGermany: 3

Description:
WZB 117 is a GLUT inhibitor (Ki(app) = 0.2, 10 and 10 μM for GLUT4, GLUT1 and GLUT3, respectively) that inhibits passive glucose transport in human erythrocytes and cancer cell lines. It decreases extracellular lactate and intracellular ATP levels. WZB 117 was shown to attenuate erythrocyte 3-O-metylglucose (3MG) uptake in vitro (Ki = 6 μM) and inhibits tumor growth in a nude mouse model.

• Molecular Weight:368.31
• Purity:≥98% by HPLC

Molecular Formula:
C20H13FO6
Canonical SMILES:
C1=CC(=CC(=C1)O)C(=O)OC2=C(C(=CC=C2)F)OC(=O)C3=CC(=CC=C3)O
InChI:
InChI=1S/C20H13FO6/c21-16-8-3-9-17(26-19(24)12-4-1-6-14(22)10-12)18(16)27-20(25)13-5-2-7-15(23)11-13/h1-11,22-23H
InChIKey:
FRSWCCBXIHFKKY-UHFFFAOYSA-N
Synonyms:
WZB117; WZB-117; WZB 117; 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate)